Sr. Bioinformatics engineer

Cambridge UK or fully remote (worldwide)

About this role:

In this role you will be responsible for designing and implementing bioinformatics tools and scalable pipelines for the analysis of pathogen genome sequencing data. The output of these tools and pipelines will be used by various customers, such as academic & diagnostic labs, healthcare clinics and pharmaceutical companies. Our customers will access the results of this analysis via an interactive web-based application which is a sophisticated scientific decision-support tool that will help provide answers to important questions such as which antibiotic will or will not work, what genes and mutations are responsible for this and how one can improve antimicrobial therapy. It is your chance to join a team of world-leading scientists and engineers in this space, help us revolutionize pathogen diagnostics, and eventually save thousands of lives.

While we welcome applications from candidates with knowledge of mechanisms of antimicrobial resistance, it is not a requirement for this role as it is solely focused on the delivery of good-quality bioinformatic tools and pipelines.

Skills and experience, Essential:

  • Understanding of genome sequencing technologies (Illumina, Oxford Nanopore, PacBio), the data they generate and biases they can introduce

  • Experience working with tools for most common layers of sequencing data processing and analysis (QC, mapping, assembly, annotation, variant calling, comparison)

  • Experience in using cloud platforms for processing and storage of the data (AWS, GCP)

  • Experience working with scalable pipeline frameworks (Nextflow)

  • Knowledge and experience working with public bioinformatics databases and archives 

  • Experience in programming languages such as Python 

  • Relational databases SQL (MySQL, Postgres) 

Skills and experience, Desired:

  • Relevant education (Bioinformatics, genetics, computer science & information technology)

  • Participation in creation of custom bioinformatic tools

  • Testing automation platforms (Gitlab CI/CD, Jenkins)

  • Linux and containeresation

  • Experience with Jira & GitLab or similar software

  • Version control with Git and gitflow

  • Self-management and motivation

  • Excellent English communication skills

  • Knowledge of mechanisms of antimicrobial resistance and experience working with bacterial genome is not required but is a plus

Benefits:

  • Competitive salary

  • Generous options scheme

  • Hybrid home/office or fully remote way of working

  • Professional development support (relevant conferences and courses)

  • 25 days holiday allowance + bank holidays